Environment-Sensitive Fluorescent Probe: A Benzophosphole Oxide with an Electron-Donating Substituent

Papers published
Eriko Yamaguchi, Chenguang Wang, Aiko Fukazawa*, Masayasu Taki, Yoshikatsu Sato, Taeko Sasaki, Minako Ueda, Narie Sasaki, Tetsuya Higashiyama,* and Shigehiro Yamaguchi,* Angew. Chem. Int. Ed., 2015, Early View. DOI: 10.1002/anie.201500229
  • The combination of an electron-accepting benzophosphole oxide with an electron-donating (diphenylamino)phenyl group led to a fluorescent compound with high fluorescence quantum yields. The benzophosphole oxide exhibited a change in fluorescence emission as a function of the solvent polarity, and was used to stain adipocytes, thus allowing discrimination of the polarity of subcellular compartments based on fluorescence.

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